MicrobiologybioRxivPreprint
Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion.
Tahseen Raza, Erich Allen Peterson, Jason Liem, Jia Liu
This study characterizes the infection defect of a myxoma virus mutant lacking M062R, showing it fails to suppress host protein synthesis and activates antiviral responses through SAMD9 pathway activation.