Author

Eva Porlan

Consejo Superior de Investigaciones CientíficasORCID 0000-0003-0934-9711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Isabel FariñasiD· 3 shared Ana L. Barrios-Muñoz· 2 shared Antonio Jordán‐PlaiD· 2 shared Coral López-FonsecaiD· 2 shared José Manuel Morante‐RedolatiD· 2 shared Teresa IglesiasiD· 2 shared Alonso M. HigueroiD· 1 shared Ana del PuertoiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Isabel FariñasORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 14, 2026

Polo-like kinase 1 controls activation of adult neural stem cells and represents a druggable entry-point to boost adult neurogenesis

Ana L. Barrios-Muñoz, Coral López-Fonseca, Elena Gutiérrez-Galindo…·Eva Porlan

This study identifies Polo-like kinase 1 (Plk1) as a regulator of adult neural stem cell quiescence and activation, showing that its inhibition enhances neurogenesis.

DOI 10.64898/2026.05.12.724486

mouseproteomics

𝕏 PostBluesky

NeuroscienceCell Death and DiseasePeer-reviewedAug 4, 2023

Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis

Ana del Puerto, Coral López-Fonseca, Ana Simón‐García…·Eva Porlan

This study identifies Kidins220 as critical for NSC survival and adult neurogenesis by regulating AKT and GSK3 activity in response to growth factors.

11 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceCellular and Molecular Life SciencesPeer-reviewedJan 1, 2023

The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2

Ana Domingo-Muelas, José Manuel Morante‐Redolat, Verónica Moncho-Amor…·Isabel Fariñas

This study shows p27 represses SOX2 and its downstream targets to regulate cell cycle exit in adult neurogenesis and oligodendrogenesis.

10 citations

mousebulk RNA-seq

𝕏 PostBluesky