Author

Martin J Blackledge

Centre National de la Recherche ScientifiqueORCID 0000-0003-0935-721XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

Aldo R. Camacho‐ZarcoiD· 1 shared Benoît ArragainiD· 1 shared Damien Maurin· 1 shared Emmi A. Mikkola· 1 shared Jacqueline TognettiiD· 1 shared Luiza Mamigonian BessaiD· 1 shared Maiia BotovaiD· 1 shared Martin PelosseiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Aldo R. Camacho‐ZarcoORCID

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2 papers

Recent·Most cited

BiochemistryScience AdvancesPeer-reviewedAug 2, 2024

A specific phosphorylation-dependent conformational switch of SARS-CoV-2 nucleoprotein inhibits RNA binding

Maiia Botova, Aldo R. Camacho‐Zarco, Jacqueline Tognetti…·Martin J Blackledge

This study identifies a phosphorylation-dependent conformational switch in SARS-CoV-2 nucleoprotein that inhibits RNA binding by altering domain interactions.

42 citationstop 1%

virusprotein structure

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Molecular BiologybioRxivPreprintApr 20, 2024

Structures of influenza A and B replication complexes explain avian to human host adaption and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.

Benoît Arragain, Tim Krischuns, Martin Pelosse…·S. Cusack

The paper reveals ANP32's role as an electrostatic chaperone stabilizing influenza polymerase complexes, explaining host adaptation and providing structural insights into replication complexes.

2 citations

experimental assay

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