Martin Pelosse

This study shows that ANP32 is a conserved host factor for viral replication in the Articulavirales order, using structural and biochemical analyses of TiLV and its interaction with ANP32.

This study determines the structure of AcMNPV nucleocapsid using CryoEM, revealing DNA portal organization and packaging apparatus features.

The paper describes the cryo-EM structure of TiLV nucleoprotein bound to RNA, revealing its RNA-binding mechanism and structural conservation across Articulavirales.

The paper introduces biGMamAct, a system for efficiently integrating large DNA cargoes at the ACTB locus using CRISPR/Cas9, demonstrating its use in expressing multiple fluorescent proteins and visualizing subcellular compartments.

The paper reveals ANP32's role as an electrostatic chaperone stabilizing influenza polymerase complexes, explaining host adaptation and providing structural insights into replication complexes.

This paper develops a baculovirus-based system for delivering large DNA cargoes for CRISPR-based genome editing in human cells, achieving up to 30% correct interventions.

The paper investigates why iron-sulphur cluster enzymes are often inactive when heterologously expressed in E. coli and identifies strategies to improve their functionality.