Judith J M Jans

This study shows that VPS41 loss causes iron overload, oxidative stress, and mitochondrial fragmentation, leading to ferroptosis and neurodegeneration.

The paper develops a metabolite signature to predict post-weaning diarrhoea in pigs using mass spectrometry and machine learning, but finds no consistent pathway enrichment.

The paper develops a tagless LysoIP method to isolate lysosomes from clinical samples and human cell lines, revealing glycerophosphodiesters as potential biomarkers for lysosomal storage disorders.

This study identifies mitochondrial and metabolic disturbances in sensory neurons as key factors in the transition from acute to chronic pain following inflammation.

MetaboShiny provides an interactive tool for analyzing and annotating direct infusion metabolomics data, demonstrating its use on lung cancer urine samples.