Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson's disease and Dementia with Lewy bodies
D. J. Vidyadhara, David C. Bäckström, Risha Chakraborty…·Sreeganga S. Chandra
This study shows that GBA mutations cause cognitive deficits in Parkinson's disease and Dementia with Lewy Bodies through synaptic vesicle endocytosis defects, independent of alpha-synuclein pathology.