Author

Benjamin N. Fry

Dana-Farber Cancer InstituteORCID 0000-0003-0981-9605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:protein structure· 2 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Organism:human· 1 Assay:protein sequence· 1

Frequent Co-Authors

Nicholas F. PolizziiD· 2 shared Daniel T.D. JonesiD· 1 shared Edmund R.S. KunjiiD· 1 shared Elena T. KaemmereriD· 1 shared Fiona FitzpatrickiD· 1 shared Hannah AguirreiD· 1 shared Kaia SlawiD· 1 shared Luise E. VeelkeniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Nicholas F. PolizziORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 21, 2026

Molecular basis of mitochondrial leucine transport by human Sideroflexin 1

Fiona Fitzpatrick, Daniel T.D. Jones, Hannah Aguirre…·Nora Kory

The paper identifies leucine as the substrate for SFXN1 and reveals its alternating-access transport mechanism using structural and biochemical analyses.

1 citation

humanprotein structure

𝕏 PostBluesky

BioengineeringNaturePeer-reviewedJun 24, 2026

Zero-shot design of drug-binding proteins via neural selection-expansion

Benjamin N. Fry, Kaia Slaw, Nicholas F. Polizzi

This paper introduces a method using two neural networks to design drug-binding proteins with high affinity, surpassing current state-of-the-art methods.

10 citationstop 1%

protein structureprotein sequence

𝕏 PostBluesky