Wenting Wu

This study identifies sex-specific islet responses to inflammation and shows that estrogen reduces inflammatory signaling and promotes immune tolerance in beta cells, contributing to sex differences in type 1 diabetes susceptibility.

This study shows that GPER signaling maintains β cell identity in female mice, and its loss during menopause may contribute to β cell dysfunction and T2D risk.

This study shows that HDI sodium butyrate improves β cell function and calcium signaling in diabetes by restoring STIM1 and SOCE, and inhibiting GSK-3 through AKT.

This study identifies somatic copy number variants (sCNVs) in schizophrenia cases, revealing their contribution to risk and specific NRXN1 disruptions.

This study identifies eight genome-wide significant CNV loci associated with schizophrenia using a large cohort of 41,321 subjects.