Eric Gracey

This study creates a cellular atlas of synovium in human and mouse knee osteoarthritis, identifying BHLHE40 as a key regulator of fibroblast activation and fibrosis.

This study uses multi-omic approaches to analyze cellular and transcriptomic diversity in infrapatellar fat pad during knee osteoarthritis, identifying fibroblasts as key contributors to disease-related differences.

This study identifies GDF15 as a mediator of inflammation-associated bone loss via a brain-bone axis, showing it induces bone loss through GFRAL receptor activation in the hindbrain.