Pratibha Potla

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis

This study identifies EphB4 as a critical mediator of pulmonary fibrosis through genetic and pharmacological approaches, showing reduced ECM gene expression and fibrotic pathology.

A cell atlas of human and mouse synovium from early and advanced stages of knee osteoarthritis: BHLHE40 regulates fibroblast activation

This study creates a cellular atlas of synovium in human and mouse knee osteoarthritis, identifying BHLHE40 as a key regulator of fibroblast activation and fibrosis.

Circulating miR-126-3p is a mechanistic biomarker for knee osteoarthritis

This study identifies miR-126-3p as a biomarker for knee osteoarthritis, showing elevated levels in patients and reduced disease severity with mimic treatment.

Cell and Transcriptomic Diversity of Infrapatellar Fat Pad during Knee Osteoarthritis

This study uses multi-omic approaches to analyze cellular and transcriptomic diversity in infrapatellar fat pad during knee osteoarthritis, identifying fibroblasts as key contributors to disease-related differences.