Rui Dong

DrugMap quantitatively analyzes cysteine ligandability across 416 cancer cell lines, revealing redox state, conformational changes, and mutations as drivers of variability, and identifies covalent inhibitors targeting NFκB1 and SOX10.

SpatialDWLS improves accuracy and speed in deconvolving spatial transcriptomic data, revealing spatial-temporal cell-type changes in human heart development.

Giotto is a toolbox for analyzing and visualizing spatial transcriptomic and proteomic data, offering integration with single-cell RNA-seq and supporting diverse datasets.

GiniClust3 identifies rare cell types in large single-cell RNA sequencing datasets efficiently and robustly.

The paper introduces CLEAR, a pipeline to compare circular and linear RNA expression using RNA-seq data by calculating CIRCscore.