Comprehensive multi-site profiling of the malignant pleural mesothelioma micro-environment identifies candidate molecular determinants of histopathologic type
David T. Severson, Samuel T. Freyaldenhoven, Benjamin J. Wadowski, Yin Pun Hung, Travis K. Hughes, Beow Yong Yeap, William G. Richards, Sanna Laaksonen, Lucian R. Chirieac, Matthew Brian Couger, Roderick V. Jensen, Ahmed A. Sadek, Ilkka Ilonen, Kimberly Vermilya, Simona Innocenti, , Raphael Bueno
This study uses single-cell RNA-sequencing and other omics data to analyze the molecular features of pleural mesothelioma subtypes and identify potential drivers of tumor cell states.
Journal of Thoracic Oncology · Nov 28, 2025Peer-reviewedCancer Biology