Author

Mehdi Shafiei Aporvari

University of Illinois ChicagoORCID 0000-0003-0993-5737Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Alisha BudhathokiiD· 1 shared Arad Abazari· 1 shared Dinitha Yasas Caldera· 1 shared Filmon Alem Medhanie· 1 shared Ganesh Pandey· 1 shared Jan-Hendrik SpilleiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

Alisha BudhathokiORCID

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1 paper

Recent·Most cited

Cell BiologyFrontiers in BiophysicsPeer-reviewedAug 19, 2026

IDRs lead the way: Cooperativity between intrinsically disordered regions and structured interaction domains drives enrichment in transcription condensates

Arad Abazari, Dinitha Yasas Caldera, Alisha Budhathoki…·Jan-Hendrik Spille

The paper shows that intrinsically disordered regions (IDRs) alone are insufficient to explain the enrichment of full-length transcription proteins in condensates, suggesting a need for structured domains in binding interactions.

DOI 10.3389/frbis.2026.1891221

proteomicsexperimental assay

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