Author

Manuel Sarmiento Soto

Consejo Superior de Investigaciones CientíficasORCID 0000-0003-0997-0153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

Jose Luis VeneroiD· 3 shared Alberto Rivera-RamosiD· 2 shared Juan García‐RevillaiD· 2 shared Rocío RuiziD· 2 shared Alberto Machado· 1 shared Alice LouailiD· 1 shared Amaia San Juan· 1 shared Amaia Vilas‐ZornozaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Jose Luis VeneroORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 18, 2025

Metabolic and transcriptional adaptations to phagocytosis in microglia sustain their functionality and regenerative properties

Mar Márquez-Ropero, Jorge Valero, Xabier Cuesta‐Puente…·Amanda Sierra

The paper investigates metabolic and transcriptional changes in microglia after phagocytosis, showing these adaptations sustain their functionality and regenerative properties.

2 citations

mousescRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 13, 2023

Galectin-3 depletion tames pro-tumoural microglia and restrains cancer cells growth

Luis Cruz-Hernández, María Teresa Sánchez Montero, Alberto Rivera-Ramos…·Manuel Sarmiento Soto

This study shows that Galectin-3 depletion reduces immunosuppressive microglia and limits cancer cell growth in brain tumours.

DOI 10.1101/2023.11.13.563707

humanexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 26, 2022

INFLAMMATORY BOWEL DISEASE INDUCES α-SYNUCLEIN AGGREGATION IN GUT AND BRAIN

Ana M. Espinosa‐Oliva, Rocío Ruiz, Manuel Sarmiento Soto…·Rocío M. de Pablos

This study shows that inflammatory bowel disease (IBD) leads to α-synuclein aggregation in the gut and brain, supporting Braak's hypothesis of Parkinson's disease origin in the enteric nervous system.

4 citations

humanrat

𝕏 PostBluesky