Carbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome
Alexandra J. Malbon, Alicja Czopek, Andrew Michael Beekman, Zoë Rachael Goddard, Aileen Boyle, Jessica Ruth Ivy, Kevin Stewart, Scott G. Denham, Joanna P. Simpson, Natalie Z M Homer, Brian Robert Walker, Neeraj Dhaun, Matthew A. Bailey, Ruth A. Morgan
This study identifies CBR1 as a regulator of blood pressure in Down Syndrome, showing that its inhibition can increase blood pressure in a DS mouse model.
Bioscience Reports · Jan 27, 2025Peer-reviewedPhysiology