GeneticsbioRxivPreprint
Time- and cell-dependent atypia and cell death are caused by progressive deficiency in DNA replication
Alex Y. Lin, Georgia K. Thomas, Khai Chung Ang…·Keith C. Cheng
This study shows that a zebrafish DNA polymerase mutation leads to DNA damage, S phase arrest, and cell death over time, with effects varying by cell type and replication rate.
4 citations