Christian D. Lorenz

This study uses AlphaFold3 to predict 3D structures of all 14 human ZIP family zinc transporters, revealing structural features and zinc-binding motifs that explain their transport mechanisms.

This study uses molecular dynamics simulations to analyze how TREM2 mutations affect the stability of the TREM2-DAP12 complex, revealing structural impacts on neuroimmune signaling in Alzheimer's disease.

This paper uses MD simulations, NMR, and SAXS to characterise the cis and trans proline conformations of ORF6CTR from SARS-CoV-2, showing good agreement between simulations and experiments.

This paper uses multi-scale molecular dynamics simulations to study the TREM2/DAP12 transmembrane domain complex formation and its role in Alzheimer's disease.

This study determines the crystal structure of Legionella collagen-like protein and reveals its unique binding mechanism for sulphated glycosaminoglycans.

This study uses unsupervised learning and molecular dynamics to show that mixing two AMPs reduces their conformational diversity and alters aggregation behavior, revealing how synergy influences their structural dynamics.