Author

Wolfgang Maret

King's College LondonORCID 0000-0003-1458-8231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1

Frequent Co-Authors

Adam P. CribbsiD· 1 shared Anvesha Saxena· 1 shared Charlotte PalmeriD· 1 shared Christer HögstrandiD· 1 shared Christian D. LorenziD· 1 shared Clarence YappiD· 1 shared Deborah H. BrothertoniD· 1 shared Edward S. HookwayiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Adam P. CribbsORCID

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2 papers

Recent·Most cited

Cell BiologyRSC Chemical BiologyPeer-reviewedJan 1, 2026

The KDM6 histone demethylase inhibitor GSK-J4 induces metal and stress responses in multiple myeloma cells

Adam P. Cribbs, Edward S. Hookway, Clarence Yapp…·Udo C. T. Oppermann

This study shows GSK-J4, a KDM6 inhibitor, induces metal and stress responses in multiple myeloma cells by increasing intracellular Zn2+ and activating metallothionein gene expression.

DOI 10.1039/d6cb00162a

humanbulk RNA-seq

𝕏 PostBluesky

BiochemistrybioRxivPreprintAug 9, 2025

Structures and zinc ion transport pathways of the human SLC39A family of metal transporters

Xilan Wang, Christian D. Lorenz, Christer Högstrand, Wolfgang Maret

This study uses AlphaFold3 to predict 3D structures of all 14 human ZIP family zinc transporters, revealing structural features and zinc-binding motifs that explain their transport mechanisms.

1 citation

humanprotein structure

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