Author

Tiago Leão

Scripps Institution of OceanographyORCID 0000-0003-1034-9153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Lena G. GerwickiD· 3 shared Pieter C. DorresteiniD· 3 shared William H. GerwickiD· 3 shared Alexey A. GurevichiD· 2 shared Evgenia GlukhoviD· 2 shared Nathan A. Moss· 2 shared Raphael ReheriD· 2 shared Alexander ShlemoviD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersBioinformatics

Lena G. GerwickORCID

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3 papers

Recent·Most cited

BioinformaticsPNAS NexusPeer-reviewedNov 1, 2022

NPOmix: a machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters

Tiago Leão, Mingxun Wang, Ricardo Silva…·Pieter C. Dorrestein

NPOmix connects mass spectrometry fragmentation data to biosynthetic gene clusters using a k-nearest neighbor classifier, improving metabolite discovery and structure prediction.

32 citations

bacteria (other)metabolomics

𝕏 PostBluesky

Synthetic BiologyACS Synthetic BiologyPeer-reviewedNov 12, 2020

Heterologous expression of cryptomaldamide in a cyanobacterial host

Arnaud Taton, Andrew K. Ecker, Brienna Diaz…·James W. Golden

This paper develops genetic tools for heterologous expression of biosynthetic gene clusters in cyanobacteria, enabling high-titer production of cryptomaldamide in Anabaena.

40 citationstop 5%

experimental assay

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BioinformaticsbioRxivPreprintDec 3, 2017

MetaRiPPquest: A Peptidogenomics Approach for the Discovery of Ribosomally Synthesized and Post-translationally Modified Peptides

Hosein Mohimani, Alexey A. Gurevich, Kelsey L. Alexander…·Pavel A. Pevzner

MetaRiPPquest identifies RiPPs by combining genome/metagenome mining with mass spectrometry analysis, discovering 5 novel natural products from 6 datasets.

4 citations

metagenomicsstatistical model

𝕏 PostBluesky