Raphael Reher

This paper discovers NHAP, a fungal metabolite that selectively inhibits Gi-signaling, demonstrating functional blockade in cardiomyocytes without cytotoxicity.

NPOmix connects mass spectrometry fragmentation data to biosynthetic gene clusters using a k-nearest neighbor classifier, improving metabolite discovery and structure prediction.

This study uses native metabolomics to identify a family of protease inhibitors from cyanobacteria, revealing their structure and potent biological activity.

MassQL, an open-source query language, lets users search raw mass spectrometry data from any vendor for isotope, fragmentation and neutral-loss patterns, from one file to entire public repositories.

CANOPUS is a tool that predicts compound classes from fragmentation spectra, enabling annotation of unknown compounds without reference data.

This paper develops genetic tools for heterologous expression of biosynthetic gene clusters in cyanobacteria, enabling high-titer production of cryptomaldamide in Anabaena.