Yvan M. Vachez

This study shows pramipexole reduces impulsivity in highly impulsive rats by modulating frontostriatal networks, specifically through Zif268 mRNA downregulation in the nucleus accumbens core.

This study shows that oral oxycodone self-administration in mice leads to features of opioid addiction, including escalation, dependence, and relapse behavior.

This study shows that obese mice exhibit increased activity in D1R-expressing spiny projection neurons in the nucleus accumbens during food seeking, which enhances food motivation and contributes to diet-induced obesity.

This paper introduces an oral oxycodone self-administration paradigm in mice to model prescription opioid use and its transition to abuse.

This study identifies a specific subpopulation of ventral pallidal neurons that modulate nucleus accumbens firing to enhance reward consumption.

This study compares the effects of unilateral and bilateral subthalamic nucleus deep brain stimulation on apathy, depression, and anxiety in Parkinson's disease using pre-clinical and clinical approaches.