BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7)
Isabella Jaen Maisonet, Mona Sharafi, Emilie J. Korchak…·Sara J. Buhrlage
This study identifies and characterizes MS-8, a small-molecule activator of USP7, showing it activates mutant USP7 in a cellular context and impacts downstream proteins.
6 citations