Author

Darius A. Paduch

Cornell UniversityORCID 0000-0003-1105-3493Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander Bolyakov· 1 shared Andrew GrimsoniD· 1 shared Anna Mielnik· 1 shared Brian D. RobinsoniD· 1 shared Francesca KhaniiD· 1 shared Jennifer K. GrenieriD· 1 shared John C. SchimentiiD· 1 shared Nathan PalmeriD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Alexander Bolyakov

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2 papers

Recent·Most cited

GeneticsDevelopmentPeer-reviewedJan 1, 2019

CDK2 kinase activity is a regulator of male germ cell fate

Priti Singh, Ravi K. Patel, Nathan Palmer…·John C. Schimenti

This study shows that CDK2 kinase activity regulates male germ cell fate by controlling the balance between stem cell renewal and differentiation, with loss of function leading to infertility.

23 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintJul 8, 2018

YBX2 Dysregulation is a Potential Cause for Late Maturation Arrest in Men with Non-Obstructive Azoospermia

Ryan Kendrick Flannigan, Anna Mielnik, Brian D. Robinson…·Darius A. Paduch

The paper investigates YBX2 dysregulation in human testis samples and finds reduced YBX2 and PRM1/2 mRNA in maturation arrest, linked to COMP levels and impaired spermatogenesis.

DOI 10.1101/364968

humanbulk RNA-seq

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