Author

Yana Ruchiy

Karolinska InstitutetORCID 0000-0003-1119-7809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alejandro Lastra RomeroiD· 2 shared Klas BlomgreniD· 2 shared Adamantia F. FragopoulouiD· 1 shared Ahmed M. OsmaniD· 1 shared Alia ShamikhiD· 1 shared André FisahniD· 1 shared Arturo G. IslaiD· 1 shared Bertrand JosephiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alejandro Lastra RomeroORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 15, 2025

Microglia Adopt Temporally Specific States after Irradiation, Correlating with Neuronal Asynchrony

Alejandro Lastra Romero, Efthalia Preka, Giusy Pizzirusso…·Klas Blomgren

This study tracks microglial state changes and neuronal asynchrony after irradiation in mice, showing delayed microglial responses and two phases of neuronal dysfunction.

DOI 10.1101/2025.02.15.638339

mousebulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedFeb 13, 2025

Unraveling Microglial Spatial Organization in the Developing Human Brain with DeepCellMap, a Deep Learning Approach Coupled to Spatial Statistics

Theo Perochon, Željka Krsnik, Marco Massimo…·David Holcman

The paper introduces DeepCellMap, a deep learning tool for analyzing spatial cellular organization in developing brains, revealing microglial phenotypes and spatial clustering patterns.

7 citations

humanspatial transcriptomics

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