Giusy Pizzirusso

This study shows that reducing H3K4 methylation in specific brain regions causes neurodevelopmental disorder-like phenotypes, including seizures, growth issues, and behavioral deficits.

This study shows AD mutations impair neural stem cell fate and early brain development, leading to structural vulnerabilities that may increase AD risk later in life.

This study tracks microglial state changes and neuronal asynchrony after irradiation in mice, showing delayed microglial responses and two phases of neuronal dysfunction.

The paper investigates how microglia loss in the hippocampus contributes to early amyloid pathology progression by disrupting neural oscillations and synaptic function in a mouse model.