Author

Marco Massimo

King's College LondonORCID 0000-0002-4082-6558Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Katherine R. LongiD· 2 shared Abigail Bennington· 1 shared Adam El Khouja· 1 shared Alejandro Lastra RomeroiD· 1 shared Catherine B. LawrenceiD· 1 shared Christopher HoyleiD· 1 shared David A. MenassaiD· 1 shared David HolcmaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Katherine R. LongORCID

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2 papers

Recent·Most cited

25-hydroxycholesterol promotes brain endothelial dysfunction by remodelling cholesterol metabolism

Víctor S. Tapia, Sarah E. Withers, Ran Zhou, Abigail Bennington, Christopher Hoyle, Frances Hedley, Adam El Khouja, Nadim Luka, Marco Massimo, Siobhan Crilly, Katherine R. Long, Catherine B. Lawrence, Paul R. Kasher

The paper shows that 25-hydroxycholesterol disrupts brain endothelial function by altering cholesterol metabolism, linking viral infection to brain vessel dysfunction in intracerebral haemorrhage.

Disease Models & Mechanisms · May 23, 2025Peer-reviewedNeuroscience

Unraveling Microglial Spatial Organization in the Developing Human Brain with DeepCellMap, a Deep Learning Approach Coupled to Spatial Statistics

Theo Perochon, Željka Krsnik, Marco Massimo, Yana Ruchiy, Alejandro Lastra Romero, Elyas Mohammadi, Xiaofei Li, Katherine R. Long, Laura Parkkinen, Klas Blomgren, Thibault Lagache, David A. Menassa, David Holcman

The paper introduces DeepCellMap, a deep learning tool for analyzing spatial cellular organization in developing brains, revealing microglial phenotypes and spatial clustering patterns.

Nature Communications · Feb 13, 2025Peer-reviewedDevelopmental Biology