Cláudio M. Soares

The paper identifies a mutation that improves PET degradation efficiency in enzyme variants through computational design and experimental validation.

This study shows that iron binding to caspofungin reduces its antifungal efficacy against Candida albicans and other fungi in iron-overloaded conditions.

GDEE is a platform for gene discovery and enzyme engineering that optimizes enzymes for biosynthetic pathways by integrating sequence analysis, structure prediction, docking, and machine learning.