Yasunori Kogure

PRCGAP provides a haplotype-resolved analysis of cancer genomes, detecting variants missed by standard references and revealing new insights into structural variants and fusion events in leukemia.

The paper identifies a neuroimmune signature in HTLV-1 infection that correlates with disease progression and severity using bulk and single-cell transcriptomic data.

This study identifies FDXR upregulation as a prognostic marker and therapeutic target in HTLV-1-associated ATL, showing its link to disease severity and sensitivity to fluorouracil.

This study identifies hyperactive PLCG1 mutations in T-cell leukemia/lymphoma that drive non-canonical signaling, enhancing cell survival and drug resistance.

The paper identifies and characterizes splicing-associated variants in cancer using a statistical framework applied to 8,976 samples across 31 cancer types, revealing 14,438 SAVs and their association with smoking and tumor suppressors.