Author

Trevor Ridgley

University of California, Los AngelesORCID 0000-0003-1177-9956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Peter ChovaneciD· 2 shared Yi A. YiniD· 2 shared Shiyang HeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersGenomics

Peter ChovanecORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 24, 2026

Robust Chromosome Segmentation in Sparse Single-Cell Whole-Genome Sequencing Using a k-Segment Constrained Hidden Markov Model

Trevor Ridgley, Peter Chovanec, Shiyang He, Yi A. Yin

The paper develops a k-segment constrained HMM for LOH detection in sparse single-cell WGS data, achieving high recall and precision.

DOI 10.64898/2026.10.19.760240

humanwhole-genome sequencing

𝕏 PostBluesky

GenomicsNucleic Acids ResearchPeer-reviewedJan 31, 2026

High-throughput mapping of spontaneous mitotic crossover and genome instability events with sci-L3-Strand-seq

Peter Chovanec, Trevor Ridgley, Yi Yin

This paper introduces sci-L3-Strand-seq, a method for high-throughput mapping of mitotic crossover and genome instability events in single cells, and demonstrates its ability to distinguish crossover types and explore genomic features.

7 citationstop 1%

scRNA-seqlong-read sequencing

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