Ehsan Motazedi

This study identifies 52 genetic variants associated with adolescent-onset depression through a large GWAS, revealing age-specific mechanisms and potential drug targets.

This study uses genome-wide meta-regression to analyze social behavior across different contexts, ages, and reporters, identifying six genetic loci and showing modest heritability.

The paper uses a multivariate GWAS approach to identify 780 genetic loci associated with cortical morphology, showing a 10-fold increase in loci compared to univariate methods.

This paper introduces PopPoly, a method for estimating polyploid haplotypes and improving genotype dosage in F1-populations using short sequence reads and pedigree information.

TriPoly improves haplotype estimation in polyploids using parent-offspring trios and Mendelian inheritance, achieving higher accuracy at lower coverage than single-individual methods.

This study evaluates polyploid haplotyping methods using a simulation pipeline, finding that sequencing depth is key and all methods struggle with higher ploidy levels.