Author

Donghyuk Kim

University of California San DiegoORCID 0000-0003-1209-0974Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Anand V. SastryiD· 3 shared Bernhard Ørn PalssoniD· 3 shared Ye GaoiD· 3 shared Jonathan M. MonkiD· 2 shared Kumari Sonal ChoudharyiD· 2 shared Laurence YangiD· 2 shared Richard SzubiniD· 2 shared Sang Woo SeoiD· 2 shared

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2018-2020 · peak 1/yr

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10 top collaborators · 44 mutual co-author links

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3 shared papersSystems Biology

Anand V. SastryORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintMay 21, 2020

Reconstruction of Fur pan-regulon uncovers the complexity and diversity of transcriptional regulation in E. coli

Ye Gao, Ina Bang, Yara Seif…·Bernhard Ørn Palsson

The paper reconstructs the Fur pan-regulon in E. coli strains, revealing core, accessory, and unique regulons and their functional diversity.

DOI 10.1101/2020.05.21.109694

E. coliChIP-seq

𝕏 PostBluesky

Systems BiologyNature CommunicationsPeer-reviewedDec 4, 2019

The Escherichia coli Transcriptome Mostly Consists of Independently Regulated Modules

Anand V. Sastry, Ye Gao, Richard Szubin…·Bernhard Ørn Palsson

The paper decomposes the Escherichia coli transcriptome into 70 independent regulatory signals, showing that 50 correspond to known transcriptional regulators and revealing a principle of signal summation in prokaryotic gene regulation.

229 citationstop 2%

E. colibulk RNA-seq

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Systems BiologybioRxivPreprintJul 17, 2018

Cellular responses to reactive oxygen species can be predicted on multiple biological scales from molecular mechanisms

Laurence Yang, Nathan Mih, Amitesh Anand…·Bernhard Ørn Palsson

The paper develops a quantitative framework to predict ROS stress responses in E. coli across molecular, network, and genetic levels.

4 citations

E. colistatistical model

𝕏 PostBluesky