Amitesh Anand

The paper investigates how alternative respiratory electron transport pathways affect aminoglycoside susceptibility in bacteria.

This study shows that E. coli lacking NADH dehydrogenases adapts by derepressing malate:quinone oxidoreductase, restoring oxidative metabolism through an alternative respiratory pathway.

This study shows that nicotinamide treatment reduces gut dysbiosis in middle-aged rodents with a history of neonatal maternal separation.

This study shows that immunometabolites like nitrate or fumarate extend mycobacterial biofilm lifespan by suppressing dormancy and maintaining metabolic activity.

This study shows how E. coli uses different oxidative stress tolerance strategies based on stress magnitude, revealing modular defense programs.

The paper identifies an aerobicity stimulon in E. coli through computational analysis of evolved respiratory variants, showing gene groups co-regulated with aerobic capacity and proteome reallocation.

The paper uses Hidden Markov Models to analyze prokaryotic genomes and reveals the widespread presence and evolutionary patterns of Complex I.

The paper uses adaptive laboratory evolution and transcriptomic analysis to identify six mechanisms of paraquat tolerance in E. coli.

The paper evolves ETS variants in E. coli and finds they all optimize growth rate and proteome allocation, with conserved aero-type strategies except for ETS-4H.

The paper develops a quantitative framework to predict ROS stress responses in E. coli across molecular, network, and genetic levels.