Feng Cao

The paper uses temporal single-cell RNA sequencing to study Calca neurons in mice and identifies BDNF as a key driver of persistent nociplastic pain.

This study shows that gustatory thalamic neurons mediate aversive behaviors by responding to noxious stimuli and fear memory, with chemogenetic and optogenetic manipulation affecting aversive responses.

This study shows that activation of parabrachial Calca neurons is necessary for chronic pain after nerve ligation and sufficient to drive nociplasticity in mice.

This study identifies Calca neurons in the parabrachial nucleus as mediators of second-order conditioning in mice through calcium imaging and chemogenetic inhibition.