Giuseppe Gasparre

This study shows that inhibiting respiratory complex I reduces tumor growth and enhances sensitivity to anti-angiogenic therapy in high-grade serous ovarian cancer.

This study identifies miR-6850 as a tumor-suppressive miRNA in high-grade serous ovarian cancer, showing its anti-oncogenic effects and potential as a biomarker and therapeutic target.

This study creates a new mouse model with a patient-derived SCA28 mutation and shows it leads to late-onset ataxia and mitochondrial dysfunction.

HmtVar is a database of over 30,000 human mitochondrial variants with pathogenicity predictions, integrating data from HmtDB and third-party annotations.