Jon Sporring A

This paper demonstrates the application of Hierarchical Phase-Contrast Tomography (HiP-CT) in three biomedical case studies, revealing detailed organ structures at multiple scales.

This study uses Light Sheet Fluorescence Microscopy to analyze 3D kidney morphology in ADPKD mouse models, identifying biomarkers of tissue deformation.

The paper uses imaging and ultrastructural analysis to show that astrocytic engagement of synapses is impaired in a mouse model of Huntington disease, contributing to synaptic dysfunction and hyperexcitability.

The paper presents a semi-automatic method for 3D reconstruction of mitochondria and cristae from 2D EM images, offering more accurate characterization of mitochondrial ultrastructure than 2D approaches.