Tsuyoshi Shuto

This paper shows that Porphyromonas gingivalis gingipain products induce CCL20 signaling and γδ T-cell accumulation in COPD-like airways via PAR-2 activation.

This study shows that high-fat diet worsens obstructive lung injury by impairing epithelial IGF-1-Akt signaling and promoting epithelial-endothelial interactions.

The paper identifies HDAC3 inhibition as a method to stabilize the IL-37 receptor module and enhance anti-inflammatory signaling in CF airway epithelial cells.

This study shows early apelin receptor activation reduces emphysema in mice by limiting inflammation and airspace enlargement, but has no effect after disease onset.