Author

Najet Srairi‐Abid

Institut Pasteur de TunisORCID 0000-0003-1296-0909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Organism:human· 1 Approach:simulation· 1

Frequent Co-Authors

Houcemeddine OthmaniD· 2 shared Kaïs GhediraiD· 2 shared Avani Bharuthram· 1 shared Florette Kathleen TreurnichtiD· 1 shared Haifa Ben MessaoudiD· 1 shared Hazem Ben Mabrouk· 1 shared Ikechukwu AchilonuiD· 1 shared Jean‐Tristan BrandenburgiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Houcemeddine OthmanORCID

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2 papers

Recent·Most cited

BioinformaticsFrontiers in Molecular BiosciencesPeer-reviewedFeb 14, 2022

SARS-CoV-2 spike protein unlikely to bind to integrins via the Arg-Gly-Asp (RGD) motif of the Receptor Binding Domain: evidence from structural analysis and microscale accelerated molecular dynamics

Houcemeddine Othman, Haifa Ben Messaoud, Oussema Khamessi…·Najet Srairi‐Abid

This study investigates whether the RGD motif in SARS-CoV-2 RBD can bind integrins using structural analysis and simulations, finding no significant conformational changes or interaction capability.

22 citations

protein structurestatistical model

𝕏 PostBluesky

BioinformaticsBiochemical and Biophysical Research CommunicationsPeer-reviewedMay 14, 2020

Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism

Houcemeddine Othman, Zied Bouslama, Jean‐Tristan Brandenburg…·Scott Hazelhurst

The paper analyzes the interaction between SARS-CoV-2 RBD and ACE2, identifies key residues for binding, and assesses the impact of ACE2 variants on this interaction.

146 citationstop 3%

humanprotein structure

𝕏 PostBluesky