NeuroscienceMolecular BrainPeer-reviewed
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism
Ozan Baytaş, Shawn M. Davidson, Julie A. Kauer, Eric M. Morrow
This study shows that loss of GPT2 in mice disrupts glutamate metabolism and synaptic transmission, with rescue by alpha-ketoglutarate supplementation.
4 citations