Andrea Talenti

This study links geography and mutation profiles in goat species, finding strong correlations between specific mutations and geographic coordinates.

The paper creates a high-resolution cattle regulatory variant atlas and identifies cross-species activity in human cells, highlighting both conservation and species-specific effects.

This study compares genomic selection accuracy and bias between pedigree-based and marker-based models in Pekin ducks, finding higher accuracy and lower bias with genomic methods for traits with low heritability.

XPCLRS detects selection signatures by improving the speed and scalability of the XP-CLR method, enabling efficient analysis of large genomic datasets.

This paper uses genotype imputation to analyze low coverage ancient goat genomes, revealing demographic patterns and genetic consequences of domestication.

The paper develops a tailored variant filtering method for multi-breed and multi-species SNP datasets to reduce bias from standard approaches.

This study develops a workflow to analyze mutation spectra across mammals, finding convergent evolution in mutation rates among species.

This study constructs a water buffalo pangenome using graph genomics, revealing extensive structural variation and population-specific selection signatures in 711 global samples.

This paper develops a framework to predict regulatory variants in cattle using machine learning, achieving high performance and demonstrating enrichment for functional variants linked to important traits.

This study presents a continent-wide genomic analysis of African buffalo, revealing three main lineages and signatures of selection related to immune response.

mutyper assigns mutation types to SNP data using ancestral genome estimates and computes mutation spectra for individuals and populations.

This study uses optical mapping to identify structural variants in cattle breeds, providing a database for further genetic and evolutionary studies.

This study identifies human functional variants with conserved effects in livestock species, showing their utility for understanding disease mechanisms.

The paper identifies a genetic locus associated with tolerance to Theileria parva infection in cattle, showing a strong heritability and replication across cohorts.

The paper creates a graph genome incorporating global cattle diversity, showing it includes more sequence and improves mapping and variant calling.

This study examines sexual differences in genetic architecture across 530 traits in 450,000 UK Biobank individuals, finding sex-specific heritability and genetic correlations.

nf-LO provides a scalable, containerised workflow for performing genome-to-genome lift over between any species with available assemblies.