PhysiologybioRxivPreprint
Evidence that the monoamine oxidase B (MAO-B) plays a central role in the inotropic dysfunction induced by genetic deletion of the Mas-related-G protein-coupled receptor D (MrgD) in mice
Lucas Rodrigues‐Ribeiro, Júlia Rezende-Ribeiro, Sérgio Scalzo…·Thiago Verano‐Braga
This study identifies MAO-B hyperactivation as a key contributor to cardiac dysfunction in MrgD-KO mice, showing that MAO-B inhibition reverses contractile defects.
DOI 10.1101/2024.03.27.586916