Fábio César Sousa Nogueira

The paper compares sample preparation workflows and homology-driven search strategies to characterize the proteome of a marine sponge, finding S-Trap with homology layers provides the most comprehensive and consistent results.

The paper compares proteomic profiles of hiPSC-derived neural stem cells in 2D monolayers and 3D neurospheres, finding neurospheres show neural pathway enrichment and increased neuronal identity.

The paper compares proteomic complexity across human neural models, finding increased molecular complexity in tissue-like models that better reflect in vivo brain biology.

This paper identifies potential drug targets and predicts treatment efficacy and resistance in melanoma subtypes using proteogenomic data and drug sensitivity analysis.

The paper identifies six proteins that predict response to immune checkpoint therapy across three melanoma cohorts and correlate with patient survival.

This study identifies MAO-B hyperactivation as a key contributor to cardiac dysfunction in MrgD-KO mice, showing that MAO-B inhibition reverses contractile defects.

This study identifies candidate proteins associated with popcorn expansion capacity using proteomic analysis of pericarp tissues from two inbred lines with differing expansion volumes.

This study quantifies proteomic changes during human neurosphere differentiation, identifying upregulated axon guidance pathways and a functional assay for neurite outgrowth.

This study integrates transcriptomic, proteomic, and genomic data from CZS neonates to identify collagen gene reductions and associated polymorphisms, linking them to neuronal migration defects and CZS susceptibility.