Author

Darren Plant

University of ManchesterORCID 0000-0003-1395-9344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 1 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne C BartoniD· 2 shared Akari SuzukiiD· 1 shared Akira Murasawa· 1 shared Alex J. MacGregoriD· 1 shared Amr Mohammed· 1 shared Amy P. WebsteriD· 1 shared Andrew FeberiD· 1 shared Atsushi KumanogohiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Anne C BartonORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintFeb 17, 2025

Proteomic characterisation of the early rheumatoid arthritis-cardiovascular disease multimorbid axis.

Rudresh R Shukla, Amr Mohammed, Nicholas Black…·Maya H Buch

This study identifies blood-based proteins associated with cardiovascular abnormalities in early rheumatoid arthritis using proteomic analysis and CMR imaging.

DOI 10.1101/2025.02.17.638761

humanproteomics

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintDec 1, 2021

Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis

Kazuyoshi Ishigaki, Saori Sakaue, Chikashi C. Terao…·Soumya Raychaudhuri

This study conducts a trans-ancestry GWAS of rheumatoid arthritis, identifying 124 loci, 34 novel, and shows improved polygenic risk score performance across populations.

13 citations

humanGWAS summary statistics

𝕏 PostBluesky

GenomicsGenome MedicinePeer-reviewedAug 10, 2018

Increased DNA methylation variability in rheumatoid arthritis discordant monozygotic twins

Amy P. Webster, Darren Plant, Simone Ecker…·Jane Worthington

The paper identifies a differentially variable DNA methylation signature in rheumatoid arthritis discordant monozygotic twins, suggesting epigenetic variability contributes to autoimmune disease.

103 citationstop 3%

humanDNA methylation

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