Andrew Feber

This study investigates whether donor DNA methylation can predict acute graft-versus-host disease (aGVHD) in HCT, finding that a classifier developed from methylation data failed to validate in an independent cohort.

The paper benchmarks five DNA methylation platforms and shows imputation improves interoperability between them.

This paper introduces CAMDAC, a method to deconvolve tumor-normal DNA methylation profiles while accounting for copy number changes, revealing epigenetic instability and distinct patterns in lung cancer.

The paper identifies a differentially variable DNA methylation signature in rheumatoid arthritis discordant monozygotic twins, suggesting epigenetic variability contributes to autoimmune disease.