Author

Jeanine M.L. Roodhart

Utrecht UniversityORCID 0000-0003-1398-8970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Angelo D. Meringa· 2 shared Dennis X. BeringeriD· 2 shared Jurgen H. E. KuballiD· 2 shared Lucrezia C D E Gatti· 2 shared Maarten A. HuismansiD· 2 shared Péter BrázdaiD· 2 shared Tineke Aarts‐Riemens· 2 shared Trudy StraetemansiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Angelo D. Meringa

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 19, 2025

Functional γδT-omics pipeline reveals compartmentalization of Vδ1⁺ T cell migration, tumor-reactivity, and clonality in human colorectal cancer

Lucrezia C D E Gatti, Mara J.T. Nicolasen, Farid Keramati…·Jurgen H. E. Kuball

The paper develops a γδT-omics pipeline to analyze compartmentalization of Vδ1⁺ T cell migration, tumor-reactivity, and clonality in human colorectal cancer, revealing distinct functional and transcriptional features across tumor compartments.

DOI 10.1101/2025.08.19.671055

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintNov 19, 2024

Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis

Astrid Cleven, Angelo D. Meringa, Péter Brázda…·Zsolt Sebestyén

This study shows that single mutations during early oncogenesis can upregulate BTN2A1, enabling Vγ9Vδ2 TCR binding, but full activation requires subsequent phosphorylation of BTN3A1.

4 citations

humanexperimental assay

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