Yang Sun

This study identifies ABCF1 as a host protein that interacts with cccDNA, forming phase-separated condensates to suppress HBV replication through innate immune activation and transcription inhibition.

This study identifies SHP2-driven endothelial activation as a key driver of estradiol-independent endometrial sterile inflammation and shows that targeting SHP2 can alleviate endometrial hyperplasia in mice.

This study creates a single-cell regulomic and transcriptomic map of cynomolgus monkeys, revealing cell-type similarities to humans over mice.