Rati Ram SHARMA

Deep-Pose-Tracker automates C. elegans behavior analysis by detecting poses and quantifying locomotion and posture features from videos.

This study develops a theoretical framework to understand how AFD neurons in C. elegans encode temperature signals and modulate responses based on prior environmental experiences.

This study identifies gcy-18 and gcy-23 as key regulators of heat stress response in C. elegans by modulating heat shock genes and proteostasis in distal tissues.

This study models mRNA translation with extrinsic noise and shows that translation initiation rate noise broadens mRNA residence time distributions, while slow codons increase residence times and mask extrinsic noise effects.

The paper develops two mathematical models of the heat shock response to study how protein folding and aggregation compete under stress, showing bistability and the role of HSF and HSF-HSP complex in refolding proteins.