NeuroscienceExperimental NeurologyPeer-reviewed
Viral overexpression of human alpha-synuclein in mouse substantia nigra dopamine neurons results in hyperdopaminergia but no neurodegeneration
Sofia Ines Garcia Moreno, Fabian Limani, Iina Ludwig…·Thomas Steinkellner
This study overexpresses human alpha-synuclein in mouse dopamine neurons and finds increased dopamine levels and activity without neurodegeneration.
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