Molecular BiologybioRxivPreprint
Dcaf17 knockdown integrates mitochondrial-lysosomal dysfunction with ferroptosis, NLRP3 inflammasome signaling and necroptosis
Nadya Al‐Yacoub, Falah Almohanna, Alanoud Alqassem…·Abdullah M. Assiri
This study shows that DCAF17 knockdown causes mitochondrial-lysosomal dysfunction, ferroptosis, NLRP3 inflammasome activation, and necroptosis in spermatogonia, linking these processes to male infertility.
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