Author

Junbin Qian

VIB-KU Leuven Center for Cancer BiologyORCID 0000-0003-1483-1836Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Diether LambrechtsiD· 2 shared Abhishek D. Garg· 1 shared Anna Timmerman· 1 shared Ayse Bassez· 1 shared Bernard ThienpontiD· 1 shared Bert Malengier-Devlies· 1 shared Bram BoeckxiD· 1 shared Christophe DoomsiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Diether LambrechtsORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 26, 2024

Case-specific selection of batch correction methods for integrating single-cell transcriptomic data from different sources

Xiaoyue Hu, Li He, Ming Chen…·Hangjin Jiang

This paper introduces RBET, a statistical framework to evaluate batch correction methods for single-cell transcriptomic data integration, showing it selects optimal tools for accurate downstream analysis.

DOI 10.1101/2024.05.26.595911

scRNA-seqstatistical model

𝕏 PostBluesky

GenomicsGenome biologyPeer-reviewedJul 27, 2020

DNA Methylation Repels Binding of HIF Transcription Factors to Maintain Tumour Immunotolerance

Flora D’Anna, Laurien Van Dyck, Jieyi Xiong…·Diether Lambrechts

The paper shows DNA methylation prevents HIF binding, affecting hypoxia responses and tumour immunotolerance.

77 citationstop 4%

humanDNA methylation

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ImmunologybioRxivJul 9, 2020

Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages

Els Wauters, Pierre Van Mol, Abhishek D. Garg…·Diether Lambrechts

This study uses single-cell profiling of bronchoalveolar lavages to compare immune responses in mild and critical COVID-19, identifying differences in T-cell function and macrophage differentiation that correlate with disease severity.

DOI 10.1038/s41422-020-00455-9

humanscRNA-seq

𝕏 PostBluesky