Molecular BiologyCell ReportsPeer-reviewed
Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
Agnes Karasik, Hernán Lorenzi, Andrew V. DePass, Nicholas R. Guydosh
The paper shows that RNase L-mediated RNA fragmentation during the innate immune response triggers antiviral outcomes through ZAK signaling and inhibits translation of stress-responsive genes.
22 citations